See our new brochure on how to integrate PIRCHE in today’s routine.
This year’s European Immunogenetics and Histocompatibility Conference in Venice is over. What a great meeting. We thank all of you who approached us at our booth, attended our presentations or took a look at the posters involving PIRCHE. Furthermore, we would like to thank all the authors and co-authors who were working on different projects […]
Every two years, the Nederlandse Transplantatie Vereniging (NTV) awards the best dissertation in the field of kidney transplantation with the Jon J. van Rood prize. This years’ winner of the award is Kirsten Geneugelijk of the Laboratorium voor Translationele Immunologie (LTI) of the University Medical Center Utrecht (UMCU) for her thesis “Indirect recognition of HLA […]
Transplant Campus is a German web portal providing knowledge and a community for professionals in transplant medicine. In its Journal Club, the editorial board regularly reviews interesting publications about current developments in the field. We are happy to announce, Transplant Campus featured the publication of Nils Lachmann et al on the effect of PIRCHE-II in […]
We are very happy to announce, that the Dutch Society for Immunology (NVVI) awarded the Medical Immunology Science Award 2017 to Eric Spierings and his group for their work on PIRCHE. This not only honours the remarkable achievements of the past years, but also underlines the importance of introducing T-cell epitope matching in the field […]
At the 25th DTG (Deutsche Transplantationsgesellschaft) annual meeting in Essen, Germany, the poster titled “De novo donor-specific HLA antibodies after kidney transplantation are correlated with the number of predicted indirectly recognizable epitopes” was awarded with a poster prize. Nils Lachmann and his team of co-authors proved previous findings of Eric Spierings’ working group, that increased numbers of PIRCHE correlate with the development […]
University Medical Center (UMC) Utrecht has developed a new method to select permissible mismatches. This technology applies to hematopoietic stem cell transplantation, solid organ transplantation, and other domains improving graft acceptance and therapy effectiveness. The new technology named PIRCHE® forecasts T-cell related immune responses against HLA derived peptides after transplantation(3). In contrast to existing technologies, […]
Kirsten Thus’ poster presented at the 12th San Francisco Cord Blood Symposium shows that “Predicted Indirectly ReCognizable HLA Epitopes (PIRCHES) correlate with chronic graft-versus-host- disease and relapse-related mortality in paediatric patients after Cord Blood transplantation”. Interestingly, the risk for cGvHD is increased with more PIRCHEs presented on HLA class II whereas lower numbers of PIRCHE […]